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Corona please read very important

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Agree with all of the above. There needs to be a full lockdown

As silly as it this might sound I wonder if the choice of words could be softer, the choice of the word "lockdown" especially; who came up with that, governments or newspapers?

VIRUS, QUARANTINE, LOCKDOWN! no wonder people panic and panic buy

Imagine a headline "UK postpones social gatherings for four weeks"

That sounds much more palatable
 
Is there any particular advantage to using oral spray over tablets? Easier to digest perhaps, or maybe faster working?

It's much better for people with IBS or gastric issues because you absorb it directly into your blood stream via soft tissue in your mouth

I've read studies that you only absorb 10% of the supplements you swallow vs 30% with an oral spray (via both absorption in the mouth than the the rest you swallow)

Personally I'm a baby with swallowing so taking sprays is far superior option, I have a lot of the BetterYou ones and couldn't recommend them enough
 
In this present crisis, people with lesser chronic illnesses are (in some cases) dying: not because they were going to die anyway, but because once this particular virus takes hold, their particular body systems get overwhelmed.
You're stating this as fact. What figures do you have that support it please?

Fair point - we don't have specific case by case details.

However, we can draw likely conclusions from reasonable facts we have.

What we know is that people fall very seriously ill with this virus, and may die, predominantly through symptoms like pneumonia leading to melt down in the lungs, and wider knock on effects. (Once o2 levels collapse in the body, the whole system is in critical danger of closing down rapidly.)

Now - while people with the most serious health conditions are clearly vulnerable - a whole wider range of people are vulnerable to pneumonia and the viral invasion that then infects the lungs. You don't need to be on death's doorstep, or have the worst cardio-thoracic conditions to be susceptible to pneumonia. I expect many of us know friends who have had pneumonia, or have had it ourselves. But once pneumonia kicks in, with this very invasive virus, you're in potential trouble. That could be a person with asthma. It could be a lifelong smoker, with compromised lung capacity. It could be a whole range of people with "underlying health conditions".

Yes, the older and more frail you are, and the worse your existing health, the less resilient you will be to fight the virus once your lungs are in trouble.

But I strongly suspect that people "with underlying health conditions" which are not in themselves that extreme may also be in real danger - just as many people (not just the sickest) can catch pneumonia.

Once this virus takes a hold, you're in trouble. Pneumonia is an early stage of it taking hold, and then it really does become a risk, as to whether your systems manage to fight back. And there's not a lot of time to do so. You need acute care 'now'.

No, I do not have the stats to demonstrate who/what individual conditions have resulted in deaths. But the understanding of the process, and how this virus works (which everyone is trying to get a handle on), leads me to believe that pneumonia is a huge first stage on the path to rapid death in many of these cases. And it's not just someone who needs a heart transplant who is susceptible to pneumonia. Many people, even outwardly healthy people reading here, may be susceptible to pneumonia. And once pneumonia kicks in, the virus has a platform. And then it acts very quick, and if you're not able to get acute care/ICU/CCU support, even just starting with basic oxygen support which I suspect hundreds of thousands will need, then the clock is ticking and the virus is propagating.

If you've had pneumonia in previous winters (even if you are generally not suffering from COPD and heart failure) then take care, avoid personal contact, and go safely. And please please please don't be macho or nonchalant about this, and go drinking in pubs etc because you're not worried. At present, that's the height of selfishness because you have a real risk of spreading the virus to others. We all need to be responsible for each other.

We also badly need time to resource and equip. That's why I favour more extreme lock-down measures.

On the capitalism thing, you're right, now is not the time. I do have views on economic systems, but right now... 'we're all in this together' and the priority is practical compassion and practical measures. This isn't the time for party politics or contending ideologies. This crisis - worldwide - has one over-riding imperative: to take what measures we can to limit deaths, and start to reduce the infection rates.

Personally I am desperately worried about the impact this virus may have on some African states, once this virus takes hold there.

best wishes,
Siusaidh
 
It's much better for people with IBS or gastric issues because you absorb it directly into your blood stream via soft tissue in your mouth

I've read studies that you only absorb 10% of the supplements you swallow vs 30% with an oral spray (via both absorption in the mouth than the the rest you swallow)

Personally I'm a baby with swallowing so taking sprays is far superior option, I have a lot of the BetterYou ones and couldn't recommend them enough

Thank you – that does sound good. I'll give it a try.
 
And please please please don't be macho or nonchalant about this, and go drinking in pubs etc because you're not worried. At present, that's the height of selfishness because you have a real risk of spreading the virus to others.

Spot on. And if you only pass it on to 2 other people who suffer no symptoms, that's not the end of the story. Those 2 people between them may well infect another 4, who then pass it on to 8 people, then 16, and so on.

Many of these will end up consuming scarce NHS resources, endangering NHS workers and others. Some will die.

But, hey, at least you got your trip to the pub in.
 
John P.A. Ioannidis is professor of medicine, of epidemiology and population health, of biomedical data science, and of statistics at Stanford University and co-director of Stanford’s Meta-Research Innovation Center.


Ioannidis then zooms in on the “one situation” where “an entire, closed population was tested”: the Diamond Princess cruise ship’s quarantined passengers. While the fatality rate was 1.0%, he points out, the population was largely elderly, the most at-risk demographic. Projected out onto the age structure of the U.S. population, he calculates, the death rate is more like 0.125%, with a range of 0.025% to 0.625% based on the sample size:

Projecting the Diamond Princess mortality rate onto the age structure of the U.S. population, the death rate among people infected with Covid-19 would be 0.125%. But since this estimate is based on extremely thin data — there were just seven deaths among the 700 infected passengers and crew — the real death rate could stretch from five times lower (0.025%) to five times higher (0.625%). It is also possible that some of the passengers who were infected might die later, and that tourists may have different frequencies of chronic diseases — a risk factor for worse outcomes with SARS-CoV-2 infection — than the general population. Adding these extra sources of uncertainty, reasonable estimates for the case fatality ratio in the general U.S. population vary from 0.05% to 1%.

“That huge range markedly affects how severe the pandemic is and what should be done,” Ioannidis stresses. “A population-wide case fatality rate of 0.05% is lower than seasonal influenza. If that is the true rate, locking down the world with potentially tremendous social and financial consequences may be totally irrational.
 
“one situation” where “an entire, closed population was tested”: the Diamond Princess cruise ship’s quarantined passengers.

In terms of conspiracy theories, I'd be very sympathetic to one that ship was locked down as a cruel experiment
 
Boris Johnson is closing cafes, pubs, bars, restaurants, nightclubs, theatres, gyms and leisure centres from tomorrow morning. The only exception is for takeaway food.
 
According to this Government tweet, the list of businesses that are "supposed" to close is actually more extensive:
  • Food & drink venues (but can still do takeaways)
  • Pubs, bars and clubs
  • Cinemas, theatres, concert and bingo halls
  • Spas, indoor leisure and gyms
  • Casinos & betting shops
  • Museums & galleries
Link to info: https://twitter.com/RobertJenrick/status/1241053100930207745

However, it's still not clear that it's an order to shut. Boris Johnson said that they could take enforcement action via licensing laws if necessary, but it still sounded like a "very strong suggestion" rather than an actual law. But it will still make a big difference, even if there are a few holdouts.
 
I'm not a scientist, surprise, surprise.
However I can't understand why government
didn't try to mass produce a face mask provided free
by the NHS. One mask to each person giving first
preference to the vulnerable. I know some arguments
against it but none so far have I found totally
convincing.
I saw one person on the supermarket till today wearing a mask and thought how very sensible he was. He was from china or thereabouts.
 
Thank you Greg. Very very sobering. As I said above, and others have said, this isn't 'flu'. This virus can deteriorate into a morbid pneumonia that can take hold very quickly, and once o2 is deprived from the body's cells and organs you face a cascade of further deterioration and you and the medics are in real trouble. Some people are more susceptible to pneumonia from the outset, and once that kicks in, your defences are quickly collapsing and the virus can propagate and invade. Lack of o2 to the body then triggers domino reactions in other organs, with the body system desperately trying to react to protect brain and other vital organs. You can't survive long when o2 supply collapses, even though they can try to ventilate and pressure more oxygen in. People with cardio problems may find they struggle with o2/co2 exchange, and basic o2-carrying blood to the rest of their bodies. People with lung problems or weaknesses already start with disadvantage if the virus and pneumonia advance. People who are frail and elderly may just not have the physical resilience to survive. But note to all - pneumonia is NOT only the consequence of being old, or having the worst health diseases. We all need to take care, and if not for ourselves, then to avoid spreading to others. It is impossible to know in advance who exactly will be overtaken by pneumonia, and once that happens, the virulent virus accentuates the problem, and o2 can start cutting out, even in a person who does not seem to have any significant health problems.
 

Couple of points; why is the reporter wearing a full hazmat suit whereas the anaesthetist is in a t-shirt and coat...not even a mask? And the reporter says that there's about a 50% death rate...which we know isn't true. The actual morbidity rate is actually far less than the 8% figure being used (according to the leading Italian health authority - see the report from an earlier post).
 
I believe he's referring to the closed cases in Italy which stand at 56%/44% currently.

Since it says discharged, is that 44% of people who were seriously ill enough with it to be admitted to hospital died?
 
I believe so, as there's reports the numbers could be much higher with people not admitted to hospital:
https://www.reuters.com/article/us-...ep-through-italys-nursing-homes-idUSKBN2152V0

I wonder how many of those deaths are from being overwhelmed and prioritising younger patients

If not, and they're all getting the best care possible a coin flip survival rate with medical intervention is pretty scary

^ I mean, for those who develop serious enough symptoms to be hospitalised
 
My mrs works in A+E and is intensive care trained. She reckons the stats being discussed in her hospital from the Italian experience are that of the sickest who end up in intensive care on a ventilator, 50% will die. Italy has 6 x the number of intensive care beds compared to the UK. That's going to be a problem too hence the call for more ventilators by the PM
 
My mrs works in A+E and is intensive care trained. She reckons the stats being discussed in her hospital from the Italian experience are that of the sickest who end up in intensive care on a ventilator, 50% will die. Italy has 6 x the number of intensive care beds compared to the UK. That's going to be a problem too hence the call for more ventilators by.


Give my best wishes to your Mrs and make sure she knows how much we appreciate what she does. The NHS workers are the equivalent of the military in WW2.[/QUOTE]
 
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My mrs works in A+E and is intensive care trained. She reckons the stats being discussed in her hospital from the Italian experience are that of the sickest who end up in intensive care on a ventilator, 50% will die. Italy has 6 x the number of intensive care beds compared to the UK. That's going to be a problem too hence the call for more ventilators by the PM



Give my best wishes to your Mrs and make sure she knows how much we appreciate what she does. The NHS workers are the equivalent of the military in WW2
 
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