Many people would register with only a few hundred exacts, I know Edwin would, he said that in a post the other day, I've seen others who say that they don't even look at the exact searches, even if it has none and they like the name, they would buy/reg it.
Sometimes you come across a nice looking name, but with an incredibly low exact search count, whilst I generally like names with a minimum of 1000 exacts, a nice name with lower searches is still a goer as you could seo it to better search terms anyway, just my opinion.